The Need and New Tools for Surveillance of Escherichia coli Pathogens

Asalapuram R. Pavankumar and Krishnan Sankaran*

Centre for Biotechnology, Anna University, IN-600 025 Chennai, India

Article history:

Received May 25, 2006
Accepted October 29, 2007

Key words:

Escherichia coli, diarrhoea, molecular pathogenesis, toxins, antigens, antibodies, diagnostic targets, surveillance


Among foodborne pathogens, diarrhoeagenic Escherichia coli is of major concern because of its commensal status, abundance in the natural environment, and ability to acquire virulence determinants by horizontal gene transfer from other microbes. From enterotoxigenic E. coli (ETEC) strains to the more virulent enterohemorrhagic E. coli (EHEC), the mechanisms of pathogenicity within this species are intriguing. Recent advances in molecular diagnostics are providing novel tools for improved rapid detection and quantification of this and other pathogenic bacteria from clinical, food, and environmental specimens. These include simple and inexpensive colorimetric and immunological methods to more elaborate nucleic acid-based assays that combine extreme specificity to unparalleled sensitivity and high sample throughput. This review summarizes the current state of E. coli pathogenesis with emphasis on the need for incorporating detection and surveillance tools as part of pre- and post-harvest food safety ideals.

*Corresponding author: ,
                                               ++91 44 22 542 298
                                               ++91 44 22 350 299

Follow us

 facebook 1 twitter bird_icon LI In Bug


Environmental Policy

sdg publishers compact 4 300x300

QR Code


We use cookies to improve our website and your experience when using it. Cookies used for the essential operation of the site have already been set. To find out more about the cookies we use and how to delete them, see our privacy policy.

I accept cookies from this site.

EU Cookie Directive Module Information